The sustainable development goals (SDGs) have marked a new era in global development-to strive towards a healthier, fairer, and safer world by 2030. Improving the health and well-being of the world’s people is at the core of the SDGs and attaining universal health coverage is central to those health-related goals. But even in the short time since their endorsement, there are immense and growing challenges to achieving them. The global HIV/AIDS response is not immune to this changing landscape and there are signs that the response is faltering.

The International AIDS Society—Lancet Commission will interrogate the following questions: First, what is the future of the HIV response in a more integrated global health and development agenda? How can we bring AIDS to an end in an era in which health and development priorities are proliferating? Second, what have we learned in four decades of battling HIV/AIDS that could inform and strengthen global health more broadly? Third, what are the real threats to global health and to universal health coverage? And finally, what are the ways forward for a more unified movement to ensure sustainable health and development for all?

The Commission explores key domains in global health with relevance to HIV, and proposes ways forward for an invigorated and sustainable global health effort - including meeting the needs of women in the HIV response (p. 15).