This publication is the third volume of the USAID Health Policy Initiative’s “Investing in MENA Series.” The purpose of the curriculum is to support a sustainable HIV response in the Middle East and North Africa (MENA) Region, centered on positive leadership, women’s leadership, prevention, education, and mentorship, as well as gender equality and sensitivity. Structured as a three-day workshop, it is the first curriculum of its kinds to be implemented by and for women living with HIV in the MENA. It aims to promote the equitable and meaningful participation of women in the HIV response.