The Meri Life, Meri Choice project was developed to reduce HIV vulnerabilities of rural adolescent girls and young women in India. This was done through providing socially disadvantaged, out-of-school girls with knowledge around sexual and reproductive health, increasing their utilization of sexual health services, creating a supportive environment to reduce vulnerabilities. The Population Council evaluated the acceptability, feasibility, and effectiveness of this model using cross-sectional, quasi-experimental evaluation methods.