This brochure highlights critical issues impacting on women and girls in the context of HIV/AIDS. The publication begins with an overview of the gender dimensions of the epidemic; outlines the necessity for adopting a rights-based approach when addressing these issues; and provides key information on issues such as the disproportionate burden on women, empowering men and women to prevent HIV/AIDS, and workplace issues in the context of HIV/AIDS. Key recommendations and actions for the way forward are provided as a conclusion.